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Hacking the Genome - Designer Proteins, Elite Organisms, and You 21st Chaos Communication Congress December 27th to 29th, 2004 Berliner Congress Center, Berlin, Germany Russell Hanson russell@qiezi.net Dec 27, 2004 Outline ã Analogies – why this talk? ã 2600 article – transgenes ã Engineering proteins ã Computer tools for genome analysis ã Conclusions 2 21C3 – Berlin The Analogy
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  Hacking the Genome -Designer Proteins, Elite Organisms, and You 21st Chaos Communication Congress December 27th to 29th, 2004 Berliner Congress Center, Berlin, Germany Russell Hanson russell@qiezi.net Dec 27, 2004   21C3 –Berlin 2 Outline ãAnalogies –why this talk?ã2600 article –transgenesãEngineering proteinsãComputer tools for genome analysisãConclusions  21C3 –Berlin 3 The Analogy Instruction Pointer : Machine Code :: Ribosome : RNA 5 ÅMap Of The Large Ribosomal Subunit  21C3 –Berlin 4 The Analogies, cont. ãThe ribosome translates mRNA to polypeptides (transcription -> RNA-processing of pre-mRNA ->mRNA translation) R. Garrett et al. The Ribosome: Structure, Function, Antibiotics, and Cellular Interactions (2000) Instruction Pointer : Machine Code :: Ribosome : RNA
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